Definitely agree with "Use what works for you"

I will be going into detail on my FX chain in the next few guide posts. I can drop the template file in the next one as well.

Quick overview of the chain is:

ReaFir - remove background noise and isolate our vocals

ReaEQ - EQ the vocals to highlight our good stuff and reduce siblance - very light EQ for clean vocals.

ReaComp - compress our output to keep things from being way too loud/quiet

Another ReaComp (optional) - further reduce siblance by compressing the frequency range where the Sharp tones lives

This is my default/free REAPER chain - I personally have a subscription for Isotopes RX 8 and use some of their tools for noise removal/mouth clicks/reverb, etc.