My wife and I tend to go through this a lot. We hold onto the fact that we have each other and we enjoy doing things together. It really helps. My wife is particularly going through this right now as one of her really good friends is working through something else and just doesn't have the time to be a friend (to simplify it). My wife is actually handling it better than me, but it still breaks my heart for her. I hope one day things will resolve. At least for now she has me!