Asthma in pedatrics

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  • Asthma is a reversible obstructive airway disease characterized by swelling, secretions and airway spasm.

  • The diagnosis of asthma made using a breathing test called spirometry. As such, it is often difficult to formally diagnose young children who are not able to perform such a test.

  • This makes it difficult to distinguish between viral induced wheeze, bronchiolitis and asthma at a very young age.

  • Symptoms include: wheezing (musical sound on expiration), cough, shortness of breath

  • Common triggers include: respiratory tract infections, allergens, exercise, cold air, dust, pollen, medications (aspirin, b-blockers), passive smoking.

  • Risk factors: family history of asthma/atopy, maternal/passive smoking. Atopy - allergic rhinitis, eczema, atopic dermatitis

Diagnosis: spirometry (pre/post bronchodilator), peak expiratory flow

Treatment:

  • Treatment is based on severity of symptoms: mild, intermittent, persistent. This is based on frequency of exacerbations, the presence of interval symptoms, the amount of respiratory distress.
  • A stepwise approach should be consider based on severity:
  1. Short acting beta agonist (SABA) as needed
  2. SABA plus low dose inhaled corticosteroid (fluticasone, budesonide)
  3. SABA plus medium dose inhaled corticosteroid
  4. SABA plus medium dose ICS plus montelukast
  5. SABA plus high dose ICS plus montelukast
  6. SABA plus high dose ICS plus montelukast plus oral corticosteroid

Note that LABA (long acting beta 2 agonists) are not recommended in young children (<5 years) due to lack of evidence. In older children LABA can be used to substitute montelukasts

Additionally, childnre with severe persistent asthma with evidence of allergic sensitisation and elevated IgE - an immunomodulator (omalizumab) may be considered.

All children with diagnosis or suspected asthma should receive an asthma action plan.

Asthma in pedatrics | Ecency