negative relationship lagna,the first house, the second house, and Astrology and alcohol. Accordingly Vedic astrology, Saturn, rahu, and mars basic responsible planets for drug abusement.if a sixth house of the horoscope more chances be addicted drugs symptoms are slurred speech, loss of muscular coordination reddened eyes vomiting even if blood –borne alcohol causes coma. In Vedic astrology ,first Venus to be considered for sex, plessure ,get pleases from beautiful woman, costly wines, moon-chandra ,karaka for mind fluctuation and attraction towards drug, or wine, mars,(mangal) forces to go towards it and (lagna) all so indication the way of life. If sani is in enemy sign or house the native spoils his life by drinking alcohol too much. Sani is on guru (Jupiter) house or nakhetra or rasi the habit is to limitless .Malefics planet is 12th house, 12th house indicated to expending denotes to either gambling, womnazing,drug,smokingAlcohol,violence or pornography.