How To Cleanse Your Body, If you're feeling sluggish and under the weather, or you've had trouble losing weight you want to take off, consider cleansing your body of toxins. Cleansing the body can boost energy and mental clarity, promote weight loss, relieve pain and prevent disease. Making dietary changes, trying a fast, exercising more and living a chemical-free lifestyle are all effective ways to cleanse the body. Here's how to get started.