Greetings dear @lemouth, thank you for your valuable question, currently the use of biological products based on entomopathogenic bacteria, is a preventive method what is sought is that the bacteria are ingested by the insect so that then inside they release toxins and penetrate the cells of the intestine as mentioned in the article, But what you mention is important because according to the publication they will try to develop transgenic crops that is to manipulate the plants to inoculate the toxins extracted from the bacteria, in that sense, I do not consider it good that plants are genetically modified, because although some specialists mention that it does not cause harm to humans, we do not know what reaction can be had at the time of being manipulated.

The opposite case is the application of bacteria that carry out their natural processes when in contact with the insect without interfering directly with the crop.

So long, have a great week.