Yes! The longest study on happiness show a strong correlation between well-being and deep relationships.

As someone who's been thoroughly involved in mental health work particularly among youth, I couldn't agree more with what you're saying here. Take the drastic rise of kids with ADHD, where most of my special ed. colleagues were more curious about the genetic influences of ADHD as opposed to environmental, socio-economic, and social media/tech-driven influences.

And I've also seen how psych meds are incredibly helpful, yet it was quite problematic the way that school psychs and healthcare professionals encouraged youth to rely on them. The sole approach of having this mechanistic understanding of the mind/body doesn't consider the importance of a holistic approach which looks at everything you're talking about. And meds alone reduce complex human experiences down to what can be changed on a bio-chemical level, yet root causes of suffering and socio-economic-cultural breakdown continue to fester in society. In my experience working with youth who had crippling mental health issues, the main thing that helped was feeling like they were part of a community where they could be themselves, and where they had a safe space to go through their pain and challenges (vs. being encouraged to avoid them). Their symptoms improved with or without meds as a result.