It is easy to ask questions that are hard to answer, as he apparently is doing here. But the real world data isn't showing a lot of adverse events from the vaccine. And that is the heart of the issue, not whether they have measured spike production levels in different patients, but how many are suffering adverse events.

In fact, my recollection is that Malone himself is not recommending against adults taking the vaccine. He primarily argued against giving it to children, based on the idea that children had less bad effects from the virus itself, so he argued that the risk-benefit analysis wasn't worth it. That's still a flawed analysis, IMO, because he wasn't arguing with hard data, just a concern about unknowns, and he also ignored the potential benefits of reaching herd immunity thru vaccination. Not only direct health benefits to children (decreased chance to contract covid for all children including ones that are immunocompromised), but economic ones as well (better economy to live in, still living parents with jobs, etc).

If the risks of covid were less severe, such arguments could be made more reasonably, but when we look at the impacts, and the increasing danger of delta (and possibly worse variants), this isn't a complicated calculation.