In 2012, the world allegedly comes to an end at the hands of a "human-made" virus, ravaging the global populace and leaving only children under the age of thirteen untouched. It is at this time that vampires emerge from the recesses of the earth, likely followed by age-old horrors of the dark thought only to be myth. The vampires sweep the earth and claim it in a single violent stroke, subjugating the remnants of humanity and leading them beneath the surface to safety. This "protection" comes at the price of donating blood to their captors. At the age of twelve, Yūichirō and his friend and fellow orphan Mikaela plotted to escape along with the children in Hyakuya Orphanage. However, this resulted in their deaths and Mikaela sacrifices himself in order for Yūichirō to escape and be saved by members of the Moon Demon Company, an extermination unit of the Japanese Imperial Demon Army. Four years later, Yūichirō dedicates his life to destroy vampires and seek revenge against them for murdering his "family." At the same time, it is revealed that Mikaela is still alive and is a vampire that Yūichirō has sworn to exterminate.
On an Earth-like world where people with superpowers known as "Quirks"(Kosei) are the norm, Izuku Midoriya is a regular middle school student who has dreams of one day becoming a Hero despite being bullied by his classmates for not having a Quirk. After being the only one to try and save his childhood bully Katsuki from a Villain, the world's greatest Hero All Might bestows upon him his own quirk "One For All". The story follows Izuku's entrance into U.A. High School (Yūei Kōkō), a school that cultivates the next generation of Super Heroes.
The series focuses on Monkey D. Luffy, a young man who, inspired by his childhood idol and powerful pirate "Red Haired" Shanks, sets off on a journey from the East Blue Sea to find the famed treasure One Piece and proclaim himself the King of the Pirates. In an effort to organize his own crew, the Straw Hat Pirates (Mugiwara Kaizoku-dan), Luffy rescues and befriends a swordsman named Roronoa Zoro, and they head off in search of the One Piece. They are joined in their journey by Nami, a navigator and thief; Usopp, a sniper and a liar; and Vinsmoke Sanji, a womanizing chef who is also a prince from a family of Royal Assasins. They acquire a ship named the Going Merry and engage in confrontations with notorious pirates of the East Blue. As Luffy and his crew set out on their adventures, others join the crew later in the series, including the doctor and anthropomorphized reindeer Tony Tony Chopper, an archaeologist and former assassin Nico Robin, a cyborg shipwright Franky, and skeletal musician Brook, and they also acquire a new ship named Thousand Sunny.
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