Malaria is obviously no joke. If not we'll tackled, it's a dangerous disease to have.
I have the AS gene and getting the malaria symptoms is at most 2ce a year. I can't imagine having to combat malaria every month. 🤔
Evolution as you've mentioned is something that is always bound to happen. Living things get to adapt to situations and may build immunity against certain things. This is actually the reason I try to do without drugs and let my body fight for itself. That way, it can build immunity if the case isn't a serious one.
I hope one day, malaria would be only in history books.
PS I got to your post from @dreemport