#metaanalysis

For better or worse, it liberates us from our inhibitions. Basically, GABA is the metaphorical little devil on our shoulders that says, "Why not?" and "What's the worst that could happen?"

At 500 billion cups of coffee consumed a year globally, caffeine is the world's most popular Nootropic. The more you learn about the wide spectrum of health and longevity benefits that caffeine - and,

The Mitochondria that drive our trillions of individual cells and define the grace with which we age have been a particularly hot arena of scientific research over the past few years. CoQ10 stands out

This Japanese-developed Racetam is one of the latest nootropics to be inspired by Piracetam - the original smart drug. According to ScienceGuy, who spent $16,000 to create the initial batch of the stuff...

Bacopa is another historical Adaptogenic herb; it has been used in India as a form of Ayurvedic medicine for thousands of years. The primary value in Bacopa for Biohackers is that, unlike other adaptogenic

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This amino acid consistently increases the levels of the "feel-good" neurotransmitter Serotonin and that's not always a good thing. It's a mood normalizer; if your mood is down and you're depressed,

A building block of several neurotransmitters that play a key role in a limitless mind; dopamine, epinephrine, serotonin, norepinephrine, and GABA. Vitamin B6 (or Pyroxidine) is a water-soluble vitamin

The cobalamin Vitamin B12 plays an essential role in the normal functioning of the brain and human nervous system. The chemical components of B12 are actually involved in brain metabolism and the manufacture

Zinc modulates brain excitability and plays an important role in Neuroplasticity; the capacity of your mind to make new connections, master new skills, and heal itself. Zinc is found in virtually every

Resveratrol is not quite a game-changing anti-aging "super supplement," as you may have been led to believe. The first thing that many of us heard about Resveratrol is that it's the special natural

This cognitive enhancer has the highest lipophilic efficiency and is quite possibly the most powerful Racetam. As a smart drug, the primary reason to take Pramiracetam is to boost long-term memory and

Two questions I get from those new to Biohacking and who haven't yet tried smart drugs are... ❓ Which smart drugs actually work and have science behind them? ❔ Which Nootropic should I get started with?

This amino acid is a potent combatant of stress, which lowers cortisol while at the same time supporting cognitive function and aiding memory. It decreases perceived exertion and cortisol from exercise

Oxiracetam is renowned as a smart drug for instilling self-control, preventing cognitive decline, promoting memory, and imbuing enhanced powers of logic that would make a Vulcan jealous. I've been doing

A fish oil and B Vitamin cofactor with some interesting animal studies. A promising (but yet unproven) agent to improve memory via RNA mechanisms. In human studies, it has a positive effect on depression

NAC is especially useful to those who have succumbed to vice but as a general Biohack, its effect on glutathione is most interesting. Healthy people should use it episodically or cyclically because of

A crucial Nootropic mineral, a cofactor of numerous key nutrients - over 300 different chemical reactions in the human body require magnesium. As a performance enhancer, it aids sleep and alleviates symptoms

Also known as Amygdalin or Laetrile, this is a controversial compound that occurs naturally in nature in the bitter seeds of apricots, apples, and peaches. It's well worth the attention of Biohackers with

Nicotinic acid, in its various forms, is the subject of a fairly heated debate over its possibly fantastic properties when it comes to anti-aging, Schizophrenia, and alcoholism. I categorize Vitamin B3